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Potential for treatment benefit of small molecule CGRP receptor antagonist plus monoclonal antibody in migraine therapy

OBJECTIVE: To provide the first clinical report that 2 calcitonin gene-related peptide (CGRP) therapies, a small molecule CGRP receptor antagonist and an anti-CGRP receptor antibody, can be used concomitantly to treat refractory migraine. METHODS: Case reports are presented of 2 patients participati...

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Detalles Bibliográficos
Autores principales: Mullin, Kathleen, Kudrow, David, Croop, Robert, Lovegren, Meghan, Conway, Charles M., Coric, Vladimir, Lipton, Richard B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526667/
https://www.ncbi.nlm.nih.gov/pubmed/31932515
http://dx.doi.org/10.1212/WNL.0000000000008944