Inhibition of Fatty Acid Oxidation as a New Target To Treat Primary Amoebic Meningoencephalitis

Primary amoebic meningoencephalitis (PAM) is a rapidly fatal infection caused by the free-living amoeba Naegleria fowleri. The amoeba migrates along the olfactory nerve to the brain, resulting in seizures, coma, and, eventually, death. Previous research has shown that Naegleria gruberi, a close rela...

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Detalles Bibliográficos
Autores principales: Sarink, Maarten J., Tielens, Aloysius G. M., Verbon, Annelies, Sutak, Robert, van Hellemond, Jaap J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526813/
https://www.ncbi.nlm.nih.gov/pubmed/32513800
http://dx.doi.org/10.1128/AAC.00344-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526813/
https://www.ncbi.nlm.nih.gov/pubmed/32513800
http://dx.doi.org/10.1128/AAC.00344-20

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