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Inhibition of Fatty Acid Oxidation as a New Target To Treat Primary Amoebic Meningoencephalitis
Primary amoebic meningoencephalitis (PAM) is a rapidly fatal infection caused by the free-living amoeba Naegleria fowleri. The amoeba migrates along the olfactory nerve to the brain, resulting in seizures, coma, and, eventually, death. Previous research has shown that Naegleria gruberi, a close rela...
Autores principales: | Sarink, Maarten J., Tielens, Aloysius G. M., Verbon, Annelies, Sutak, Robert, van Hellemond, Jaap J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526813/ https://www.ncbi.nlm.nih.gov/pubmed/32513800 http://dx.doi.org/10.1128/AAC.00344-20 |
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