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Simvastatin Improves Cardiac Function through Notch 1 Activation in BALB/c Mice with Chronic Chagas Cardiomyopathy

Chagas disease, caused by the protozoan Trypanosoma cruzi, endemic in Latin America but distributed worldwide because of migration. Without appropriate treatment, the disease progresses from an acute asymptomatic phase to a chronic, progressive inflammatory cardiomyopathy causing heart failure and d...

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Detalles Bibliográficos
Autores principales: Guzmán-Rivera, Daniela, Liempi, Ana, González-Herrera, Fabiola, Fuentes-Retamal, Sebastián, Carrillo, Ileana, Abarca, Patricio, Castillo, Christian, Kemmerling, Ulrike, Pesce, Barbara, Maya, Juan Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526820/
https://www.ncbi.nlm.nih.gov/pubmed/32393497
http://dx.doi.org/10.1128/AAC.02141-19