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Knockdown of hsa_circ_0059955 Induces Apoptosis and Cell Cycle Arrest in Nucleus Pulposus Cells via Inhibiting Itchy E3 Ubiquitin Protein Ligase

BACKGROUND: Circular RNAs (circRNAs) play an important role in the progression of intervertebral disc (IVD) degeneration (IVDD). Using bioinformatics analysis, we have found that the expression of circRNA hsa_circ_0059955 was significantly downregulated in IVDD tissues. However, the relevant mechani...

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Detalles Bibliográficos
Autores principales: Kong, Daliang, Gu, Rui, Zhang, Chengtao, Yin, Ruofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526870/
https://www.ncbi.nlm.nih.gov/pubmed/33061300
http://dx.doi.org/10.2147/DDDT.S253293