Transfer of HTLV-1 p8 and Gag to target T-cells depends on VASP, a novel interaction partner of p8

The Human T-cell leukemia virus type 1 (HTLV-1) orf I-encoded accessory protein p8 is cleaved from its precursor p12, and both proteins contribute to viral persistence. p8 induces cellular protrusions, which are thought to facilitate transfer of p8 to target cells and virus transmission. Host factor...

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Detalles Bibliográficos
Autores principales: Donhauser, Norbert, Socher, Eileen, Millen, Sebastian, Heym, Stefanie, Sticht, Heinrich, Thoma-Kress, Andrea K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526893/
https://www.ncbi.nlm.nih.gov/pubmed/32997728
http://dx.doi.org/10.1371/journal.ppat.1008879

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526893/
https://www.ncbi.nlm.nih.gov/pubmed/32997728
http://dx.doi.org/10.1371/journal.ppat.1008879

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