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All-atom simulation of the HET-s prion replication

Prions are self-replicative protein particles lacking nucleic acids. Originally discovered for causing infectious neurodegenerative disorders, they have also been found to play several physiological roles in a variety of species. Functional and pathogenic prions share a common mechanism of replicati...

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Detalles Bibliográficos
Autores principales: Terruzzi, Luca, Spagnolli, Giovanni, Boldrini, Alberto, Requena, Jesús R., Biasini, Emiliano, Faccioli, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526898/
https://www.ncbi.nlm.nih.gov/pubmed/32946455
http://dx.doi.org/10.1371/journal.pcbi.1007922