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Prednisolone suppresses adriamycin-induced vascular smooth muscle cell senescence and inflammatory response via the SIRT1-AMPK signaling pathway

Cellular senescence is associated with inflammation and the senescence-associated secretory phenotype (SASP) of secreted proteins. Vascular smooth muscle cell (VSMC) expressing the SASP contributes to chronic vascular inflammation, loss of vascular function, and the developments of age-related disea...

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Detalles Bibliográficos
Autores principales: Sung, Jin Young, Kim, Seul Gi, Kim, Jae-Ryong, Choi, Hyoung Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526920/
https://www.ncbi.nlm.nih.gov/pubmed/32997729
http://dx.doi.org/10.1371/journal.pone.0239976