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Susceptibility of pentylenetetrazole-induced seizures in mice with Cereblon gene knockout

Epilepsy is a neurological disorder characterized by unpredictable seizures, which are bursts of electrical activity that tempo-rarily affect the brain. Cereblon (CRBN), a DCAFs (DDB1 and CUL4associated factors), is a well-established protein associated with human mental retardation. Being a substra...

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Detalles Bibliográficos
Autores principales: Jeon, Seung-Je, Ham, Jinsil, Park, Chul-Seung, Lee, Boreom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7526979/
https://www.ncbi.nlm.nih.gov/pubmed/32843131
http://dx.doi.org/10.5483/BMBRep.2020.53.9.119