A hidden lung cancer in a patient with granulomatosis with polyangiitis

Granulomatosis with polyangiitis is a systemic necrotizing vasculitis that affects the small- and medium-sized blood vessels. The diagnosis can be challenging since the clinical and imaging findings have similarities with infection, and malignancy. Serologic and histopathological investigations ofte...

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Autores principales: Xie, Cheng, Stoddart, Catriona, Bewes, James, Peschl, Heiko, Luqmani, Raashid, Benamore, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Institute of Radiology. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527008/
https://www.ncbi.nlm.nih.gov/pubmed/33029377
http://dx.doi.org/10.1259/bjrcr.20190114
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author Xie, Cheng
Stoddart, Catriona
Bewes, James
Peschl, Heiko
Luqmani, Raashid
Benamore, Rachel
author_facet Xie, Cheng
Stoddart, Catriona
Bewes, James
Peschl, Heiko
Luqmani, Raashid
Benamore, Rachel
author_sort Xie, Cheng
collection PubMed
description Granulomatosis with polyangiitis is a systemic necrotizing vasculitis that affects the small- and medium-sized blood vessels. The diagnosis can be challenging since the clinical and imaging findings have similarities with infection, and malignancy. Serologic and histopathological investigations often help confirm the diagnosis. However, this can be falsely reassuring. We present a unique case of the coexistence of vasculitis and squamous cell carcinoma in the same cavitating lung mass. The case highlights the importance of recognizing changes in disease behaviour early to allow for timely management.
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spelling pubmed-75270082020-10-06 A hidden lung cancer in a patient with granulomatosis with polyangiitis Xie, Cheng Stoddart, Catriona Bewes, James Peschl, Heiko Luqmani, Raashid Benamore, Rachel BJR Case Rep Case Report Granulomatosis with polyangiitis is a systemic necrotizing vasculitis that affects the small- and medium-sized blood vessels. The diagnosis can be challenging since the clinical and imaging findings have similarities with infection, and malignancy. Serologic and histopathological investigations often help confirm the diagnosis. However, this can be falsely reassuring. We present a unique case of the coexistence of vasculitis and squamous cell carcinoma in the same cavitating lung mass. The case highlights the importance of recognizing changes in disease behaviour early to allow for timely management. The British Institute of Radiology. 2020-09-29 /pmc/articles/PMC7527008/ /pubmed/33029377 http://dx.doi.org/10.1259/bjrcr.20190114 Text en © 2020 The Authors. Published by the British Institute of Radiology This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
spellingShingle Case Report
Xie, Cheng
Stoddart, Catriona
Bewes, James
Peschl, Heiko
Luqmani, Raashid
Benamore, Rachel
A hidden lung cancer in a patient with granulomatosis with polyangiitis
title A hidden lung cancer in a patient with granulomatosis with polyangiitis
title_full A hidden lung cancer in a patient with granulomatosis with polyangiitis
title_fullStr A hidden lung cancer in a patient with granulomatosis with polyangiitis
title_full_unstemmed A hidden lung cancer in a patient with granulomatosis with polyangiitis
title_short A hidden lung cancer in a patient with granulomatosis with polyangiitis
title_sort hidden lung cancer in a patient with granulomatosis with polyangiitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527008/
https://www.ncbi.nlm.nih.gov/pubmed/33029377
http://dx.doi.org/10.1259/bjrcr.20190114
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