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Structural insight into the Staphylococcus aureus ATP-driven exporter of virulent peptide toxins

Staphylococcus aureus is a major human pathogen that has acquired alarming broad-spectrum antibiotic resistance. One group of secreted toxins with key roles during infection is the phenol-soluble modulins (PSMs). PSMs are amphipathic, membrane-destructive cytolytic peptides that are exported to the...

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Detalles Bibliográficos
Autores principales: Zeytuni, N., Dickey, S. W., Hu, J., Chou, H. T., Worrall, L. J., Alexander, J. A. N., Carlson, M. L., Nosella, M., Duong, F., Yu, Z., Otto, M., Strynadka, N. C. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527219/
https://www.ncbi.nlm.nih.gov/pubmed/32998902
http://dx.doi.org/10.1126/sciadv.abb8219