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Membrane surface recognition by the ASAP1 PH domain and consequences for interactions with the small GTPase Arf1

Adenosine diphosphate–ribosylation factor (Arf) guanosine triphosphatase–activating proteins (GAPs) are enzymes that need to bind to membranes to catalyze the hydrolysis of guanosine triphosphate (GTP) bound to the small GTP-binding protein Arf. Binding of the pleckstrin homology (PH) domain of the...

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Detalles Bibliográficos
Autores principales: Soubias, Olivier, Pant, Shashank, Heinrich, Frank, Zhang, Yue, Roy, Neeladri Sekhar, Li, Jess, Jian, Xiaoying, Yohe, Marielle E., Randazzo, Paul A., Lösche, Mathias, Tajkhorshid, Emad, Byrd, R. Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527224/
https://www.ncbi.nlm.nih.gov/pubmed/32998886
http://dx.doi.org/10.1126/sciadv.abd1882