Modulation of the Promoter Activation Rate Dictates the Transcriptional Response to Graded BMP Signaling Levels in the Drosophila Embryo

Morphogen gradients specify cell fates during development, with a classic example being the bone morphogenetic protein (BMP) gradient’s conserved role in embryonic dorsal-ventral axis patterning. Here, we elucidate how the BMP gradient is interpreted in the Drosophila embryo by combining live imagin...

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Detalles Bibliográficos
Autores principales: Hoppe, Caroline, Bowles, Jonathan R., Minchington, Thomas G., Sutcliffe, Catherine, Upadhyai, Priyanka, Rattray, Magnus, Ashe, Hilary L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527239/
https://www.ncbi.nlm.nih.gov/pubmed/32758422
http://dx.doi.org/10.1016/j.devcel.2020.07.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527239/
https://www.ncbi.nlm.nih.gov/pubmed/32758422
http://dx.doi.org/10.1016/j.devcel.2020.07.007

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