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Modulation of the Promoter Activation Rate Dictates the Transcriptional Response to Graded BMP Signaling Levels in the Drosophila Embryo

Morphogen gradients specify cell fates during development, with a classic example being the bone morphogenetic protein (BMP) gradient’s conserved role in embryonic dorsal-ventral axis patterning. Here, we elucidate how the BMP gradient is interpreted in the Drosophila embryo by combining live imagin...

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Detalles Bibliográficos
Autores principales:	Hoppe, Caroline, Bowles, Jonathan R., Minchington, Thomas G., Sutcliffe, Catherine, Upadhyai, Priyanka, Rattray, Magnus, Ashe, Hilary L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527239/ https://www.ncbi.nlm.nih.gov/pubmed/32758422 http://dx.doi.org/10.1016/j.devcel.2020.07.007

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