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RORα phosphorylation by casein kinase 1α as glucose signal to regulate estrogen sulfation in human liver cells
Estrogen sulfotransferase (SULT1E1) metabolically inactivates estrogen and SULT1E1 expression is tightly regulated by multiple nuclear receptors. Human fetal, but not adult, livers express appreciable amounts of SULT1E1 protein, which is mimicked in human hepatoma-derived HepG2 cells cultured in hig...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Portland Press Ltd.
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527261/ https://www.ncbi.nlm.nih.gov/pubmed/32686824 http://dx.doi.org/10.1042/BCJ20200427 |