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Valproic acid upregulates the expression of the p75NTR/sortilin receptor complex to induce neuronal apoptosis
The antiepileptic and mood stabilizer agent valproic acid (VPA) has been shown to exert anti-tumour effects and to cause neuronal damage in the developing brain through mechanisms not completely understood. In the present study we show that prolonged exposure of SH-SY5Y and LAN-1 human neuroblastoma...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527367/ https://www.ncbi.nlm.nih.gov/pubmed/32712736 http://dx.doi.org/10.1007/s10495-020-01626-0 |