Increase in endogenous glucose production with SGLT2 inhibition is attenuated in individuals who underwent kidney transplantation and bilateral native nephrectomy

AIMS/HYPOTHESIS: The glucosuria induced by sodium–glucose cotransporter 2 (SGLT2) inhibition stimulates endogenous (hepatic) glucose production (EGP), blunting the decline in HbA(1c). We hypothesised that, in response to glucosuria, a renal signal is generated and stimulates EGP. To examine the effe...

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Detalles Bibliográficos
Autores principales: Daniele, Giuseppe, Solis-Herrera, Carolina, Dardano, Angela, Mari, Andrea, Tura, Andrea, Giusti, Laura, Kurumthodathu, Jancy J., Campi, Beatrice, Saba, Alessandro, Bianchi, Anna Maria, Tregnaghi, Carla, Egidi, Maria Francesca, Abdul-Ghani, Muhammad, DeFronzo, Ralph, Del Prato, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527374/
https://www.ncbi.nlm.nih.gov/pubmed/32827269
http://dx.doi.org/10.1007/s00125-020-05254-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527374/
https://www.ncbi.nlm.nih.gov/pubmed/32827269
http://dx.doi.org/10.1007/s00125-020-05254-w

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