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Increase in endogenous glucose production with SGLT2 inhibition is attenuated in individuals who underwent kidney transplantation and bilateral native nephrectomy
AIMS/HYPOTHESIS: The glucosuria induced by sodium–glucose cotransporter 2 (SGLT2) inhibition stimulates endogenous (hepatic) glucose production (EGP), blunting the decline in HbA(1c). We hypothesised that, in response to glucosuria, a renal signal is generated and stimulates EGP. To examine the effe...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527374/ https://www.ncbi.nlm.nih.gov/pubmed/32827269 http://dx.doi.org/10.1007/s00125-020-05254-w |