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Marine-inspired molecular mimicry generates a drug-free, but immunogenic hydrogel adhesive protecting surgical anastomosis

Herein, we report the synthesis of a biomimic hydrogel adhesive that addresses the poor healing of surgical anastomosis. Dopamine-conjugated xanthan gum (Da-g-Xan) is fabricated using deep insights into the molecular similarity between mussels' adhesive and dopamine as well as the structural si...

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Detalles Bibliográficos
Autores principales: Huang, Jinjian, Jiang, Yungang, Liu, Ye, Ren, Yanhan, Xu, Ziyan, Li, Zongan, Zhao, Yun, Wu, Xiuwen, Ren, Jianan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527377/
https://www.ncbi.nlm.nih.gov/pubmed/33024898
http://dx.doi.org/10.1016/j.bioactmat.2020.09.010