Desoxyrhapontigenin attenuates neuronal apoptosis in an isoflurane-induced neuronal injury model by modulating the TLR-4/cyclin B1/Sirt-1 pathway

This study investigated the protective effect of desoxyrhapontigenin (DOP) against isoflurane (ISF)-induced neuronal injury in rats. Neuronal injury was induced in pups by exposing them to 0.75% ISF on postnatal day 7 with 30% oxygen for 6 h. The pups were treated with DOP 10 mg/kg, i.p., for 21 day...

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Detalles Bibliográficos
Autores principales: Liang, Feng, Fu, Xin, Li, Yunpengfei, Han, Fanglei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527400/
https://www.ncbi.nlm.nih.gov/pubmed/32997222
http://dx.doi.org/10.1186/s13568-020-01105-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527400/
https://www.ncbi.nlm.nih.gov/pubmed/32997222
http://dx.doi.org/10.1186/s13568-020-01105-4

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