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Rat pancreatectomy combined with isoprenaline or uninephrectomy as models of diabetic cardiomyopathy or nephropathy

Cardiovascular and renal complications are the predominant causes of morbidity and mortality amongst patients with diabetes. Development of novel treatments have been hampered by the lack of available animal models recapitulating the human disease. We hypothesized that experimental diabetes in rats...

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Detalles Bibliográficos
Autores principales: Thisted, Louise, Østergaard, Mette V., Pedersen, Annemarie A., Pedersen, Philip J., Lindsay, Ross T., Murray, Andrew J., Fink, Lisbeth N., Pedersen, Tanja X., Secher, Thomas, Johansen, Thea T., Thrane, Sebastian T., Skarsfeldt, Torben, Jelsing, Jacob, Thomsen, Morten B., Zois, Nora E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527487/
https://www.ncbi.nlm.nih.gov/pubmed/32999377
http://dx.doi.org/10.1038/s41598-020-73046-8