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Rat pancreatectomy combined with isoprenaline or uninephrectomy as models of diabetic cardiomyopathy or nephropathy
Cardiovascular and renal complications are the predominant causes of morbidity and mortality amongst patients with diabetes. Development of novel treatments have been hampered by the lack of available animal models recapitulating the human disease. We hypothesized that experimental diabetes in rats...
Autores principales: | Thisted, Louise, Østergaard, Mette V., Pedersen, Annemarie A., Pedersen, Philip J., Lindsay, Ross T., Murray, Andrew J., Fink, Lisbeth N., Pedersen, Tanja X., Secher, Thomas, Johansen, Thea T., Thrane, Sebastian T., Skarsfeldt, Torben, Jelsing, Jacob, Thomsen, Morten B., Zois, Nora E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527487/ https://www.ncbi.nlm.nih.gov/pubmed/32999377 http://dx.doi.org/10.1038/s41598-020-73046-8 |
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