Cargando…

Identification of the dog orthologue of human MAS-related G protein coupled receptor X2 (MRGPRX2) essential for drug-induced pseudo-allergic reactions

MAS-related G protein coupled receptor-X2 (MRGPRX2), expressed in human mast cells, is associated with drug-induced pseudo-allergic reactions. Dogs are highly susceptible to drug-induced anaphylactoid reactions caused by various drugs; however, the distribution and physiological function of canine M...

Descripción completa

Detalles Bibliográficos
Autores principales: Hamamura-Yasuno, Eri, Iguchi, Takuma, Kumagai, Kazuyoshi, Tsuchiya, Yoshimi, Mori, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527510/
https://www.ncbi.nlm.nih.gov/pubmed/32999394
http://dx.doi.org/10.1038/s41598-020-72819-5