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Mutational analysis of Escherichia coli GreA protein reveals new functional activity independent of antipause and lethal when overexpressed

There is a growing appreciation for the diverse regulatory consequences of the family of proteins that bind to the secondary channel of E. coli RNA polymerase (RNAP), such as GreA, GreB or DksA. Similar binding sites could suggest a competition between them. GreA is characterised to rescue stalled R...

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Detalles Bibliográficos
Autores principales: Fernández-Coll, Llorenç, Potrykus, Katarzyna, Cashel, Michael, Balsalobre, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527559/
https://www.ncbi.nlm.nih.gov/pubmed/32999370
http://dx.doi.org/10.1038/s41598-020-73069-1