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NT5C2 methylation regulatory interplay between DNMT1 and insulin receptor in type 2 diabetes

Epigenetics alternation of non-genetic variation and genome-wide association study proven allelic variants may associate with insulin secretion in type 2 diabetes (T2D) development. We analyzed promoter DNA methylation array to evaluate the associated with increased susceptibility to T2D (30 cases,...

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Detalles Bibliográficos
Autores principales: Chen, Yng-Tay, Lin, Wei-De, Liao, Wen-Ling, Tsai, Ya-Ching, Liao, Jiunn-Wang, Tsai, Fuu-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527562/
https://www.ncbi.nlm.nih.gov/pubmed/32999320
http://dx.doi.org/10.1038/s41598-020-71336-9