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Toward diagnostic relevance of the α(V)β(5), α(V)β(3), and α(V)β(6) integrins in OA: expression within human cartilage and spinal osteophytes

We previously reported (18)FPRGD(2) uptake by the coxofemoral lining, intervertebral discs and facet joint osteophytes in OA using PET/SCAN imaging. However, the molecular mechanism by which the PRGD(2) tracer interacts with joint tissues and osteophytes in OA remains unclear. As PRGD(2) ligands are...

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Detalles Bibliográficos
Autores principales: Charlier, Edith, Deroyer, Céline, Neuville, Sophie, Plener, Zelda, Malaise, Olivier, Ciregia, Federica, Gillet, Philippe, Reuter, Gilles, Salvé, Mallory, Withofs, Nadia, Hustinx, Roland, de Seny, Dominique, Malaise, Michel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527564/
https://www.ncbi.nlm.nih.gov/pubmed/33083095
http://dx.doi.org/10.1038/s41413-020-00110-4