The Killing of Human Neuroblastoma Cells by the Small Molecule JQ1 Occurs in a p53-Dependent Manner

BACKGROUND: MYCN amplification is a prognostic biomarker associated with poor prognosis of neuroblastoma in children. The overall survival of children with MYCN-amplified neuroblastoma has only marginally improved within the last 20 years. The Bromodomain and Extra-Terminal motif (BET) inhibitor, JQ...

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Detalles Bibliográficos
Autores principales: Mazar, Joseph, Gordon, Caleb, Naga, Varun, Westmoreland, Tamarah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2020
Materias:
Pediatric
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527568/
https://www.ncbi.nlm.nih.gov/pubmed/32329693
http://dx.doi.org/10.2174/1871520620666200424123834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527568/
https://www.ncbi.nlm.nih.gov/pubmed/32329693
http://dx.doi.org/10.2174/1871520620666200424123834

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