Probing the Structure–Function relationship and amyloidogenic propensities in natural variants of apolipoprotein A-I

BACKGROUND: Apolipoprotein A-I (apoA-I) protects against atherosclerosis and participates in the removal of excess cellular cholesterol from peripheral organs. Several naturally occurring apoA-I mutations are associated with familial systemic amyloidosis, with deposition of amyloid aggregates in per...

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Detalles Bibliográficos
Autores principales: Ma'arfi, Farah, Chandra, Subhash, Fatima, Jamal e, Khan, Mohd Yasir, Mir, Snober S., Yusuf, Mohd Aslam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527581/
https://www.ncbi.nlm.nih.gov/pubmed/33024841
http://dx.doi.org/10.1016/j.bbrep.2020.100815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527581/
https://www.ncbi.nlm.nih.gov/pubmed/33024841
http://dx.doi.org/10.1016/j.bbrep.2020.100815

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