Therapeutic Targeting of Myeloperoxidase Attenuates NASH in Mice

Myeloperoxidase (MPO) activity has been associated with the metabolic syndrome, cardiovascular and liver disease. Here, we evaluate the therapeutic potential of MPO inhibition on nonalcoholic steatohepatitis (NASH) and NASH‐induced fibrosis, the main determinant of outcomes. MPO plasma levels were e...

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Detalles Bibliográficos
Autores principales: Koop, Anja Christina, Thiele, Nina Doreen, Steins, David, Michaëlsson, Erik, Wehmeyer, Malte, Scheja, Ludger, Steglich, Babett, Huber, Samuel, Schulze zur Wiesch, Julian, Lohse, Ansgar W., Heeren, Jörg, Kluwe, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527691/
https://www.ncbi.nlm.nih.gov/pubmed/33024915
http://dx.doi.org/10.1002/hep4.1566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527691/
https://www.ncbi.nlm.nih.gov/pubmed/33024915
http://dx.doi.org/10.1002/hep4.1566

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