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Therapeutic Targeting of Myeloperoxidase Attenuates NASH in Mice
Myeloperoxidase (MPO) activity has been associated with the metabolic syndrome, cardiovascular and liver disease. Here, we evaluate the therapeutic potential of MPO inhibition on nonalcoholic steatohepatitis (NASH) and NASH‐induced fibrosis, the main determinant of outcomes. MPO plasma levels were e...
Autores principales: | Koop, Anja Christina, Thiele, Nina Doreen, Steins, David, Michaëlsson, Erik, Wehmeyer, Malte, Scheja, Ludger, Steglich, Babett, Huber, Samuel, Schulze zur Wiesch, Julian, Lohse, Ansgar W., Heeren, Jörg, Kluwe, Johannes |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527691/ https://www.ncbi.nlm.nih.gov/pubmed/33024915 http://dx.doi.org/10.1002/hep4.1566 |
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