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Beyond Toxin Transport: Novel Role of ABC Transporter for Enzymatic Machinery of Cereulide NRPS Assembly Line

Nonribosomal peptide synthetases (NRPSs) and polyketide synthetases (PKSs) play a pivotal role in the production of bioactive natural products, such as antibiotics and cytotoxins. Despite biomedical and pharmaceutical importance, the molecular mechanisms and architectures of these multimodular enzym...

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Detalles Bibliográficos
Autores principales: Gacek-Matthews, A., Chromiková, Z., Sulyok, M., Lücking, G., Barák, I., Ehling-Schulz, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527721/
https://www.ncbi.nlm.nih.gov/pubmed/32994334
http://dx.doi.org/10.1128/mBio.01577-20