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Beyond Toxin Transport: Novel Role of ABC Transporter for Enzymatic Machinery of Cereulide NRPS Assembly Line
Nonribosomal peptide synthetases (NRPSs) and polyketide synthetases (PKSs) play a pivotal role in the production of bioactive natural products, such as antibiotics and cytotoxins. Despite biomedical and pharmaceutical importance, the molecular mechanisms and architectures of these multimodular enzym...
Autores principales: | Gacek-Matthews, A., Chromiková, Z., Sulyok, M., Lücking, G., Barák, I., Ehling-Schulz, M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527721/ https://www.ncbi.nlm.nih.gov/pubmed/32994334 http://dx.doi.org/10.1128/mBio.01577-20 |
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