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Klebsiella pneumoniae Reduces SUMOylation To Limit Host Defense Responses

Klebsiella pneumoniae is an important cause of multidrug-resistant infections worldwide. Understanding the virulence mechanisms of K. pneumoniae is a priority and timely to design new therapeutics. Here, we demonstrate that K. pneumoniae limits the SUMOylation of host proteins in epithelial cells an...

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Detalles Bibliográficos
Autores principales: Sá-Pessoa, Joana, Przybyszewska, Kornelia, Vasconcelos, Filipe Nuno, Dumigan, Amy, Frank, Christian G., Hobley, Laura, Bengoechea, Jose A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527722/
https://www.ncbi.nlm.nih.gov/pubmed/32994335
http://dx.doi.org/10.1128/mBio.01733-20