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Interleukin-1β Triggers p53-Mediated Downmodulation of CCR5 and HIV-1 Entry in Macrophages through MicroRNAs 103 and 107

Macrophages are a target of human immunodeficiency virus type 1 (HIV-1) and may serve as a viral reservoir during antiretroviral therapy (ART). Their susceptibility to HIV-1 infection is subject to variations from permissiveness to resistance depending on their origin, tissue localization, and polar...

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Detalles Bibliográficos
Autores principales: Lodge, Robert, Bellini, Nicolas, Laporte, Mélanie, Salahuddin, Syim, Routy, Jean-Pierre, Ancuta, Petronela, Costiniuk, Cecilia T., Jenabian, Mohammad-Ali, Cohen, Éric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527731/
https://www.ncbi.nlm.nih.gov/pubmed/32994328
http://dx.doi.org/10.1128/mBio.02314-20