A Key Motif in the Cholesterol-Dependent Cytolysins Reveals a Large Family of Related Proteins

The cholesterol-dependent cytolysins (CDCs) are bacterial, β-barrel, pore-forming toxins. A central enigma of the pore-forming mechanism is how completion of the prepore is sensed to initiate its conversion to the pore. We identified a motif that is conserved between the CDCs and a diverse family of...

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Detalles Bibliográficos
Autores principales: Evans, Jordan C., Johnstone, Bronte A., Lawrence, Sara L., Morton, Craig J., Christie, Michelle P., Parker, Michael W., Tweten, Rodney K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527733/
https://www.ncbi.nlm.nih.gov/pubmed/32994330
http://dx.doi.org/10.1128/mBio.02351-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527733/
https://www.ncbi.nlm.nih.gov/pubmed/32994330
http://dx.doi.org/10.1128/mBio.02351-20

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