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A Key Motif in the Cholesterol-Dependent Cytolysins Reveals a Large Family of Related Proteins
The cholesterol-dependent cytolysins (CDCs) are bacterial, β-barrel, pore-forming toxins. A central enigma of the pore-forming mechanism is how completion of the prepore is sensed to initiate its conversion to the pore. We identified a motif that is conserved between the CDCs and a diverse family of...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Microbiology
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527733/ https://www.ncbi.nlm.nih.gov/pubmed/32994330 http://dx.doi.org/10.1128/mBio.02351-20 |