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Rapid, redox-mediated mechanical susceptibility of the cortical microtubule lattice in skeletal muscle

The highly ordered cortical microtubule lattice of skeletal muscle is disorganized in dystrophin-deficient mdx mice. Implicated mechanisms include loss of dystrophin binding, altered α-tubulin posttranslational modification, expression of a β-tubulin involved in regeneration, and reactive oxygen spe...

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Detalles Bibliográficos
Autores principales: Nelson, D'anna M., Fasbender, Elizabeth K., Jakubiak, Margurite C., Lindsay, Angus, Lowe, Dawn A., Ervasti, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527753/
https://www.ncbi.nlm.nih.gov/pubmed/33002761
http://dx.doi.org/10.1016/j.redox.2020.101730