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Engineering of HN3 increases the tumor targeting specificity of exosomes and upgrade the anti-tumor effect of sorafenib on HuH-7 cells

Safe, efficient and cancer cell targeted delivery of CRISPR/Cas9 is important to increase the effectiveness of available cancer treatments. Although cancer derived exosomes offer significant advantages, the fact that it carries cancer related/inducing signaling molecules impedes them from being used...

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Detalles Bibliográficos
Autores principales: He, Cong, Jaffar Ali, Doulathunnisa, Li, Yumin, Zhu, Yanliang, Sun, Bo, Xiao, Zhongdang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527773/
https://www.ncbi.nlm.nih.gov/pubmed/33062407
http://dx.doi.org/10.7717/peerj.9524