The Gene-Regulatory Footprint of Aging Highlights Conserved Central Regulators

Many genes and pathways have been linked to aging, yet our understanding of underlying molecular mechanisms is still lacking. Here, we measure changes in the transcriptome, histone modifications, and DNA methylome in three metabolic tissues of adult and aged mice. Transcriptome and methylome changes...

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Detalles Bibliográficos
Autores principales: Bou Sleiman, Maroun, Jha, Pooja, Houtkooper, Riekelt, Williams, Robert W., Wang, Xu, Auwerx, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527782/
https://www.ncbi.nlm.nih.gov/pubmed/32997995
http://dx.doi.org/10.1016/j.celrep.2020.108203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527782/
https://www.ncbi.nlm.nih.gov/pubmed/32997995
http://dx.doi.org/10.1016/j.celrep.2020.108203

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