Molecular basis for the bifunctional Uba4–Urm1 sulfur‐relay system in tRNA thiolation and ubiquitin‐like conjugation

The chemical modification of tRNA bases by sulfur is crucial to tune translation and to optimize protein synthesis. In eukaryotes, the ubiquitin‐related modifier 1 (Urm1) pathway is responsible for the synthesis of 2‐thiolated wobble uridine (U(34)). During the key step of the modification cascade,...

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Detalles Bibliográficos
Autores principales: Pabis, Marta, Termathe, Martin, Ravichandran, Keerthiraju E, Kienast, Sandra D, Krutyhołowa, Rościsław, Sokołowski, Mikołaj, Jankowska, Urszula, Grudnik, Przemysław, Leidel, Sebastian A, Glatt, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527816/
https://www.ncbi.nlm.nih.gov/pubmed/32901956
http://dx.doi.org/10.15252/embj.2020105087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527816/
https://www.ncbi.nlm.nih.gov/pubmed/32901956
http://dx.doi.org/10.15252/embj.2020105087

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