Inducible TDG knockout models to study epigenetic regulation

Mechanistic and functional studies by gene disruption or editing approaches often suffer from confounding effects like compensatory cellular adaptations generated by clonal selection. These issues become particularly relevant when studying factors directly involved in genetic or epigenetic maintenan...

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Detalles Bibliográficos
Autores principales: Schwarz, Simon D., Grundbacher, Eliane, Hrovat, Alexandra M., Xu, Jianming, Kuśnierczyk, Anna, Vågbø, Cathrine B., Schär, Primo, Schuermann, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2020
Materias:
Method Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527862/
https://www.ncbi.nlm.nih.gov/pubmed/33082936
http://dx.doi.org/10.12688/f1000research.25637.2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527862/
https://www.ncbi.nlm.nih.gov/pubmed/33082936
http://dx.doi.org/10.12688/f1000research.25637.2

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