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Cucurbitacin D Induces G2/M Phase Arrest and Apoptosis via the ROS/p38 Pathway in Capan-1 Pancreatic Cancer Cell Line

Pancreatic cancer has a poor prognosis with a five-year survival rate of less than 10%. Moreover, chemotherapy is mostly rendered ineffective owing to chemotherapy resistance and cytotoxicity. Therefore, the development of effective therapeutic strategies and novel drugs against pancreatic cancer is...

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Detalles Bibliográficos
Autores principales: Kim, Myeong-Sun, Lee, Kangwook, Ku, Jin Mo, Choi, Yu-Jeong, Mok, Kyungyul, Kim, Doori, Cheon, Chunhoo, Ko, Seong-Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527894/
https://www.ncbi.nlm.nih.gov/pubmed/33029168
http://dx.doi.org/10.1155/2020/6571674