Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung

LAMP2A and HSC70 are crucial players in chaperone-mediated autophagy (CMA), a targeted, lysosome-dependent protein degradation pathway. Elevated LAMP2A levels, indicative of increased CMA activity, are observed in several malignancies, and CMA downregulation may be exploited therapeutically. We eval...

Descripción completa

Detalles Bibliográficos
Autores principales: Losmanová, Tereza, Janser, Félice A., Humbert, Magali, Tokarchuk, Igor, Schläfli, Anna M., Neppl, Christina, Schmid, Ralph A., Tschan, Mario P., Langer, Rupert, Berezowska, Sabina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527932/
https://www.ncbi.nlm.nih.gov/pubmed/33029283
http://dx.doi.org/10.1155/2020/8506572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527932/
https://www.ncbi.nlm.nih.gov/pubmed/33029283
http://dx.doi.org/10.1155/2020/8506572

Ejemplares similares