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NOTCH1 is critical for fibroblast-mediated induction of cardiomyocyte specialization into ventricular conduction system-like cells in vitro

Cardiac fibroblasts are present throughout the myocardium and are enriched in the microenvironment surrounding the ventricular conduction system (VCS). Several forms of arrhythmias are linked to VCS abnormalities, but it is still unclear whether VCS malformations are cardiomyocyte autonomous or coul...

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Detalles Bibliográficos
Autores principales: Ribeiro da Silva, Agatha, Neri, Elida A., Turaça, Lauro Thiago, Dariolli, Rafael, Fonseca-Alaniz, Miriam H., Santos-Miranda, Artur, Roman-Campos, Danilo, Venturini, Gabriela, Krieger, Jose E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527973/
https://www.ncbi.nlm.nih.gov/pubmed/32999360
http://dx.doi.org/10.1038/s41598-020-73159-0