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GALNT2 regulates ANGPTL3 cleavage in cells and in vivo of mice

Angiopoietin-like protein 3 (ANGPTL3) is an important inhibitor of lipoprotein lipase and endothelial lipase that plays critical roles in lipoprotein metabolism. It specifically expresses in the liver and undergoes proprotein convertase-mediated cleavage during secretion, which generates an N-termin...

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Detalles Bibliográficos
Autores principales: Li, Xuedan, Zhang, Yiliang, Zhang, Minzhu, Wang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527996/
https://www.ncbi.nlm.nih.gov/pubmed/32999434
http://dx.doi.org/10.1038/s41598-020-73388-3