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Cetuximab produced from a goat mammary gland expression system is equally efficacious as innovator cetuximab in animal cancer models

There is increasing demand for improved production and purification systems for biosimilar or biobetter humanised monoclonal antibodies and animal production systems offer one such possibile option. Cetuximab, also known as ‘Erbitux’, is a humanised monoclonal antibody widely used in cancer therapy....

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Detalles Bibliográficos
Autores principales: Wang, Qian, Gavin, William, Masiello, Nicholas, Tran, Khanh B., Laible, Götz, Shepherd, Peter R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528048/
https://www.ncbi.nlm.nih.gov/pubmed/33024714
http://dx.doi.org/10.1016/j.btre.2020.e00533