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Hypoxia Helps Maintain Nucleus Pulposus Homeostasis by Balancing Autophagy and Apoptosis

Intervertebral disc degeneration (IVDD) is a common cause of lower back pain. Programmed cell death (PCD) including apoptosis and autophagy is known to play key mechanistic roles in the development of IVDD. We hypothesized that the nucleus pulposus cells that make up the center of the IVD can be aff...

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Detalles Bibliográficos
Autores principales: Kim, Han-Jun, Lee, Hye-Rim, Kim, Hyosung, Do, Sun Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528147/
https://www.ncbi.nlm.nih.gov/pubmed/33029281
http://dx.doi.org/10.1155/2020/5915481