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Inhibition of phospholipase D2 augments histone deacetylase inhibitor-induced cell death in breast cancer cells

BACKGROUND: Histone deacetylase (HDAC) inhibitors are promising anticancer drugs but their effect on tumor treatment has been disappointing mainly due to the acquisition of HDAC inhibitor resistance. However, the mechanisms underlying such resistance remain unclear. METHODS: In this study, we perfor...

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Detalles Bibliográficos
Autores principales: Hwang, Won Chan, Kang, Dong Woo, Kang, Youra, Jang, Younghoon, Kim, Jung-Ae, Min, Do Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528251/
https://www.ncbi.nlm.nih.gov/pubmed/32998768
http://dx.doi.org/10.1186/s40659-020-00294-3