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Current status and future perspectives of HLA-edited induced pluripotent stem cells

In 2007, Human-induced pluripotent stem cells (iPSCs) were generated by transducing four genes (Oct3/4, Sox2, Klf4, c-Myc). Because iPSCs can differentiate into any types of cells in the body and have fewer ethical issues compared to embryonic stem (ES) cells, application of iPSCs for regenerative m...

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Detalles Bibliográficos
Autores principales: Koga, Keiko, Wang, Bo, Kaneko, Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528263/
https://www.ncbi.nlm.nih.gov/pubmed/33014207
http://dx.doi.org/10.1186/s41232-020-00132-9