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Improvement of DNA Vector Delivery of DOTAP Lipoplexes by Short-Chain Aminolipids

[Image: see text] Cellular delivery of DNA vectors for the expression of therapeutic proteins is a promising approach to treat monogenic disorders or cancer. Significant efforts in a preclinical and clinical setting have been made to develop potent nonviral gene delivery systems based on lipoplexes...

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Detalles Bibliográficos
Autores principales: Buck, Jonas, Mueller, Dennis, Mettal, Ute, Ackermann, Miriam, Grisch-Chan, Hiu Man, Thöny, Beat, Zumbuehl, Andreas, Huwyler, Jörg, Witzigmann, Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528285/
https://www.ncbi.nlm.nih.gov/pubmed/33015490
http://dx.doi.org/10.1021/acsomega.0c03303